Wednesday, May 12, 2010

Cottonseed for Cancer

No, it is not the whole cottonseed, it is a purified derivative of its extract called Gossypol. When this compound was tested against human prostate cancer in mice, the cancer was completely wiped out.

Cancer cells express proteins to resist chemotherapy and radiation, so that it can prevent cell death (apoptosis). There are 6 varieties of these anti-apoptotic proteins and they are expressed differently in different cancers. Targeting the right one protein may not be enough to kill cancer cells, as they often express more than one and can select for an "escape" protein and continue to prosper.

The new compound inhibits all six anti-apoptotic proteins. Its broad spectrum activity could make current cancer treatment more effective by preparing malignant cells to die.

Read the details ...
Cancer: Trapping the escape artist

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